NPHP4 and RBP7

Data Source:
BioGRID (biochemical)

		NPHP4	RBP7
Description		nephrocystin 4	retinol binding protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium	Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Retinal Binding Retinol Binding
	Biological Process	Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Hippo Signaling Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone
Pathways		Signaling by Hippo Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Senior-Loken syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)
Interacting Genes		2 interacting genes: NPHP1 RPGRIP1	5 interacting genes: APPL2 DAPP1 DOK4 HSH2D NCKIPSD
Entrez ID		261734	116362
HPRD ID		06238	16355
Ensembl ID		ENSG00000131697	ENSG00000162444
Uniprot IDs		B3KW36 O75161	Q96R05
PDB IDs			1LPJ 6AT8 6E6K
Enriched GO Terms of Interacting Partners?
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