NPHP4 and SCRG1

Data Source:
BioGRID (affinity chromatography technology)

		NPHP4	SCRG1
Description		nephrocystin 4	stimulator of chondrogenesis 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium	Extracellular Space Golgi Apparatus Neuron Projection Terminus
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Hippo Signaling Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone	Nervous System Development
Pathways		Signaling by Hippo Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Senior-Loken syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)	Chin dimples ( 27182965) Diverticular disease ( 30177863) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: NPHP1 RPGRIP1	4 interacting genes: CATSPER1 FAM209A MANBAL TMEM14B
Entrez ID		261734	11341
HPRD ID		06238	11932
Ensembl ID		ENSG00000131697	ENSG00000164106
Uniprot IDs		B3KW36 O75161	O75711 Q6FGG5
PDB IDs
Enriched GO Terms of Interacting Partners?
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