IFT172 and TMEM214

Data Source:
BioGRID (affinity chromatography technology)

		IFT172	TMEM214
Description		intraflagellar transport 172	transmembrane protein 214
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet Extracellular Vesicle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Microtubule Integral Component Of Membrane
	Molecular Function
	Biological Process	Neural Tube Closure Heart Looping Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Limb Development Cilium Assembly Bone Development Hindgut Development Left/right Axis Specification Non-motile Cilium Assembly	Apoptotic Process
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Total cholesterol levels ( 30718733)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: LHX3 LHX4	2 interacting genes: LSM1 PJA1
Entrez ID		26160	54867
HPRD ID		09576	07887
Ensembl ID		ENSG00000138002	ENSG00000119777
Uniprot IDs		A0A6Q8PGJ2 Q9UG01	Q6NUQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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