IFT172 and EFR3B

Data Source:
BioGRID (enzymatic study)

		IFT172	EFR3B
Description		intraflagellar transport 172	EFR3 homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet Extracellular Vesicle	Cytosol Plasma Membrane Actin Cytoskeleton
	Molecular Function		Protein Binding
	Biological Process	Neural Tube Closure Heart Looping Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Limb Development Cilium Assembly Bone Development Hindgut Development Left/right Axis Specification Non-motile Cilium Assembly	Phosphatidylinositol Phosphorylation Protein Localization To Plasma Membrane
Pathways		Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Total cholesterol levels ( 30718733)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index in non-asthmatics ( 23517042) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 28552196) Inflammatory bowel disease ( 28067908) Type 1 diabetes ( 21980299)
Interacting Genes		2 interacting genes: LHX3 LHX4
Entrez ID		26160	22979
HPRD ID		09576	13824
Ensembl ID		ENSG00000138002	ENSG00000084710
Uniprot IDs		A0A6Q8PGJ2 Q9UG01	B3KT90 E7ESK9 Q9Y2G0
PDB IDs
Enriched GO Terms of Interacting Partners?
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