NOC2L and PTGFR

Data Source:
BioGRID (two hybrid, x-ray crystallography)
HPRD (in vivo, in vitro, two hybrid)

		NOC2L	PTGFR
Description		NOC2 like nucleolar associated transcriptional repressor	prostaglandin F receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Noc1p-Noc2p Complex Noc2p-Noc3p Complex	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding Nucleosome Binding Histone Binding Repressing Transcription Factor Binding	Prostaglandin F Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Apoptotic Process Apoptotic Process Chromatin Assembly Cellular Response To UV Negative Regulation Of Histone Acetylation Ribosomal Large Subunit Biogenesis Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus
Pathways		Regulation of TP53 Activity through Phosphorylation	Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases
GWAS		California verbal learning test score ( 31596458) Pancreatic cancer ( 29422604)	Bipolar disorder ( 22182935) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		10 interacting genes: APP ATN1 ATXN7 H2AC18 H2BP1 H3-4 H4-16 LRIF1 PPP1CA RBFOX1	5 interacting genes: AGTR1 PTGDS PTGER1 PTGER2 PTGES2
Entrez ID		26155	5737
HPRD ID		13166	08988
Ensembl ID		ENSG00000188976	ENSG00000122420
Uniprot IDs		Q9Y3T9	P43088
PDB IDs
Enriched GO Terms of Interacting Partners?
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