ZBTB20 and CD47

Data Source:
HPRD (in vivo, in vitro)

		ZBTB20	CD47
Description		zinc finger and BTB domain containing 20	CD47 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Body	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glycolytic Process Positive Regulation Of Lipid Biosynthetic Process Lipid Homeostasis Cellular Response To Glucose Stimulus	Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Cell Migration Positive Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Interferon-gamma Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Monocyte Extravasation Neutrophil Degranulation Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Leukocyte Migration Positive Regulation Of Stress Fiber Assembly Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 ATP Export Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Pathways			Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Fish- and plant-related diet ( 32066663) Gastric cancer ( 22037551 31383772) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) HIV-1 viral setpoint ( 26039976) Mitochondrial DNA levels ( 25240745) Mucinous adenocarcinoma in colorectal cancer ( 29942513) Oily fish consumption ( 32066663) Platelet count ( 32888494) Plateletcrit ( 32888494) Pork consumption ( 32066663) Postoperative atrial fibrillation after cardiac surgery ( 30678657) Seasonality and depression ( 30217971) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30224653) Type 2 diabetes ( 26818947 32499647) Urate levels in obese individuals ( 25811787) Youthful appearance (self-reported) ( 32339537)	Bipolar disorder ( 31043756) Body mass index ( 25673413) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889)
Interacting Genes		2 interacting genes: NR3C1 PPARG	16 interacting genes: BNIP3 EPB42 FAS GNAI1 ITGAV MTIF3 MUC1 P2RY2 PTK2 PVR RHAG SIRPA SYNE4 THBS1 TMEM167B UBQLN1
Entrez ID		26137	961
HPRD ID		05822	03017
Ensembl ID		ENSG00000181722	ENSG00000196776
Uniprot IDs		B2RCW4 Q9HC78	A0A0A1TSG4 Q08722
PDB IDs			2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU
Enriched GO Terms of Interacting Partners?
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