SZRD1 and PADI4

Data Source:
HPRD (in vitro)

		SZRD1	PADI4
Description		SUZ RNA binding domain containing 1	peptidyl arginine deiminase 4
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex
	Molecular Function		Protein-arginine Deiminase Activity Calcium Ion Binding Protein Binding Arginine Binding Identical Protein Binding
	Biological Process		Chromatin Organization Nucleosome Assembly Chromatin Remodeling Cellular Protein Modification Process Protein Citrullination Stem Cell Population Maintenance Histone H3-R26 Citrullination Histone Citrullination Innate Immune Response
Pathways			Chromatin modifying enzymes
Drugs			Citrulline Azithromycin Tetracycline Streptomycin N-[(1S)-1-(aminocarbonyl)-4-(ethanimidoylamino)butyl]benzamide
Diseases
GWAS			Autoimmune traits (pleiotropy) ( 30572963) Basal cell carcinoma ( 18849993) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) IgA nephropathy ( 25305756) Rheumatoid arthritis ( 21452313 21505073 30423114 30572963 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		1 interacting genes: STRAP	10 interacting genes: ANXA4 APP FBXO25 H3C15 HDAC2 LRRK2 NPM1 POU6F2 SMURF1 TRIB3
Entrez ID		26099	23569
HPRD ID		13213	05635
Ensembl ID		ENSG00000055070	ENSG00000159339
Uniprot IDs		Q7Z422	Q9UM07
PDB IDs			1WD8 1WD9 1WDA 2DEW 2DEX 2DEY 2DW5 3APM 3APN 3B1T 3B1U 4DKT 4X8C 4X8G 5N0M 5N0Y 5N0Z 5N1B
Enriched GO Terms of Interacting Partners?
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