GIGYF2 and ARL4C

Data Source:
BioGRID (affinity chromatography technology)

		GIGYF2	ARL4C
Description		GRB10 interacting GYF protein 2	ADP ribosylation factor like GTPase 4C
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Protein-containing Complex Perikaryon Proximal Dendrite	Nucleus Cytoplasm Cytosol Plasma Membrane Filopodium
	Molecular Function	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding	GTPase Activity Protein Binding GTP Binding Alpha-tubulin Binding
	Biological Process	Posttranscriptional Gene Silencing Negative Regulation Of Translation Insulin-like Growth Factor Receptor Signaling Pathway MRNA Destabilization	Intracellular Protein Transport Vesicle-mediated Transport Endocytic Recycling
Pathways			NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases		Parkinson's disease (PD)
GWAS		Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Schizophrenia ( 25056061 29483656 23974872)	Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Central corneal thickness ( 29760442) Cognitive decline (age-related) ( 28078323) Initial pursuit acceleration in psychotic disorders ( 29064472) Pancreatic cancer ( 20686608) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Triglyceride levels ( 30108155)
Interacting Genes		8 interacting genes: APC CNOT9 GRB10 GRB14 GRB7 RBM12 SNRPB WBP11	2 interacting genes: APP UBQLN4
Entrez ID		26058	10123
HPRD ID		11639	11988
Ensembl ID		ENSG00000204120	ENSG00000188042
Uniprot IDs		Q6Y7W6	A0A024R4C5 P56559
PDB IDs		5NVL 5NVM
Enriched GO Terms of Interacting Partners?
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