DNAH1 and LIN7B

Data Source:
BioGRID (biochemical)

		DNAH1	LIN7B
Description		dynein axonemal heavy chain 1	lin-7 homolog B, crumbs cell polarity complex component
Image		No pdb structure
GO Annotations	Cellular Component	Axonemal Dynein Complex Microtubule Axoneme Dynein Complex Sperm Flagellum Inner Dynein Arm	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Microtubule Motor Activity ATP Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	Cilium Movement Microtubule-based Movement Sperm Axoneme Assembly Flagellated Sperm Motility Inner Dynein Arm Assembly Cilium-dependent Cell Motility	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane
Pathways			Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Chronotype ( 30696823) Electroencephalogram traits ( 25387704) HDL cholesterol ( 30275531) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)
Interacting Genes			22 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP2 MPP3 MPP7 NTAQ1 PALS1 PALS2 PSMB1 TCEANC TRAPPC12
Entrez ID		25981	64130
HPRD ID		11790	10040
Ensembl ID		ENSG00000114841	ENSG00000104863
Uniprot IDs		A0A140VJI6 Q9P2D7	Q9HAP6
PDB IDs			2DKR
Enriched GO Terms of Interacting Partners?
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