GAP43 and LOX

Data Source:
BioGRID (two hybrid)

		GAP43	LOX
Description		growth associated protein 43	lysyl oxidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Dendrite Filopodium Membrane Growth Cone Membrane Perikaryon GABA-ergic Synapse	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix
	Molecular Function	Phosphatidylserine Binding Protein Binding Calmodulin Binding Lysophosphatidic Acid Binding Phosphatidylinositol Phosphate Binding	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding
	Biological Process	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Axon Regeneration Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Regulation Of Postsynaptic Specialization Assembly	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways		L1CAM interactions	Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) Breast size ( 22747683) Metabolite levels ( 23823483) Proliferative diabetic retinopathy ( 31482010) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Seasonality and depression ( 30217971) Urate levels in obese individuals ( 25811787)	Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		8 interacting genes: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1	8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1
Entrez ID		2596	4015
HPRD ID		01198	01087
Ensembl ID		ENSG00000172020	ENSG00000113083
Uniprot IDs		P17677 Q5U058	B0AZT2 B7ZAJ4 D0PNI2 P28300
PDB IDs
Enriched GO Terms of Interacting Partners?
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