ZDHHC5 and DTX4

Data Source:
BioGRID (affinity chromatography technology)

		ZDHHC5	DTX4
Description		zinc finger DHHC-type palmitoyltransferase 5	deltex E3 ubiquitin ligase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Dendrite Phagocytic Vesicle	Nucleoplasm Cytosol
	Molecular Function	Protein Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Phosphopantetheinylation Protein Palmitoylation Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Phagocytic Vesicle	Notch Signaling Pathway Protein Ubiquitination Regulation Of Type I Interferon Production
Pathways			IRF3 mediated activation of type 1 IFN Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Schizophrenia ( 28991256 25056061 29483656)	Hepatitis B surface antigen seroclearance in chronic hepatitis B infection ( 29975729) Metabolite levels ( 23823483)
Interacting Genes		1 interacting genes: SRPK2
Entrez ID		25921	23220
HPRD ID		15720	19312
Ensembl ID		ENSG00000156599	ENSG00000110042
Uniprot IDs		A0A024R546 Q9C0B5	Q9Y2E6
PDB IDs
Enriched GO Terms of Interacting Partners?
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