DPCD and ACTR1A

Data Source:
BioGRID (proximity labelling technology)

		DPCD	ACTR1A
Description		deleted in primary ciliary dyskinesia homolog (mouse)	actin related protein 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus	Manchette Cytoplasm Centrosome Centriole Cytosol Dynactin Complex Microtubule Associated Complex Microtubule Cytoskeleton COPI-coated Vesicle Extracellular Exosome Cell Cortex Region
	Molecular Function	Protein Binding	Protein Binding ATP Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Left/right Pattern Formation	G2/M Transition Of Mitotic Cell Cycle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Spermatogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Ciliary Basal Body-plasma Membrane Docking
Pathways			MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: APP RUVBL2	5 interacting genes: DCTN1 DCTN4 NUMA1 SPTBN1 SPTBN2
Entrez ID		25911	10121
HPRD ID		13247	05507
Ensembl ID		ENSG00000166171	ENSG00000138107
Uniprot IDs		Q5JQQ4 Q9BVM2	A0A384NQ21 P61163
PDB IDs
Enriched GO Terms of Interacting Partners?
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