RPL36 and KLHL4

Data Source:
BioGRID (genetic interference)

		RPL36	KLHL4
Description		ribosomal protein L36	kelch like family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome	Cytoplasm Microtubule Cytoskeleton Centriolar Satellite
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Molecular_function Actin Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Biological_process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Alzheimer's disease ( 30636644)
Interacting Genes		4 interacting genes: APP DUX4 PTEN RPL18A
Entrez ID		25873	56062
HPRD ID		10201	02283
Ensembl ID		ENSG00000130255	ENSG00000102271
Uniprot IDs		Q9Y3U8	A5PKX1 Q9C0H6
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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