GABPA and TMPRSS15

Data Source:
BioGRID (affinity chromatography technology)

		GABPA	TMPRSS15
Description		GA binding protein transcription factor subunit alpha	transmembrane serine protease 15
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Brush Border Membrane Integral Component Of Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Activating Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Gene Expression Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dopamine	Proteolysis Endocytosis
Pathways		Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases			Enterokinase deficiency
GWAS		Gout (normal type) ( 32238385) Nicotine dependence symptom count ( 25555482)	Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)
Interacting Genes		13 interacting genes: APP ATF1 CREBBP EP300 GABPB1 GABPB2 HCFC1 MED1 PINX1 SP1 SP3 STK16 ZC2HC1B	1 interacting genes: SPINK1
Entrez ID		2551	5651
HPRD ID		11793	05972
Ensembl ID		ENSG00000154727	ENSG00000154646
Uniprot IDs		A8IE48 Q06546 Q8IYS3	P98073
PDB IDs			4DGJ 6ZOV
Enriched GO Terms of Interacting Partners?
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