YTHDF3 and MAT2B

Data Source:
BioGRID (affinity chromatography technology)

		YTHDF3	MAT2B
Description		YTH N6-methyladenosine RNA binding protein 3	methionine adenosyltransferase 2B
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytosol Methionine Adenosyltransferase Complex Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Binding	Protein Binding Enzyme Binding Methionine Adenosyltransferase Regulator Activity
	Biological Process	Positive Regulation Of Translation Positive Regulation Of Translational Initiation Negative Regulation Of Type I Interferon-mediated Signaling Pathway MRNA Destabilization	S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Methylation Regulation Of Catalytic Activity
Pathways			Methylation Ub-specific processing proteases
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body size at age 10 ( 32376654) Breakfast cereal skipping frequency ( 31190057) Breakfast skipping ( 31190057) Chronotype ( 30696823) HDL cholesterol levels ( 32203549) Myocardial infarction ( 26708285) Smoking behaviour (cigarettes smoked per day) ( 30679032) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)	Aging ( 22773346) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Broad depression or major depressive disorder (self-reported) ( 30626913) Chronotype ( 30696823) Common carotid intima-media thickness ( 29206233) General risk tolerance (MTAG) ( 30643258) Methadone dose in opioid dependence ( 28115739) Neuritic plaque ( 31497858) Number of sexual partners ( 30643258) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Smoking initiation ( 24665060) Uterine fibroid size (maximum dimension) ( 30196971) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		2 interacting genes: FAF1 ZDHHC17	10 interacting genes: APP FBXO25 HRH1 KPNA3 KPNA4 MAT2A PLA2G6 RABEP1 TEPSIN TRIM27
Entrez ID		253943	27430
HPRD ID		08106	05701
Ensembl ID		ENSG00000185728	ENSG00000038274
Uniprot IDs		A0A024R7W5 A0A087WY31 B4DPX9 Q658Z6 Q7Z739 Q8N3V9 Q8NA80	A0A140VJP2 Q9NZL9
PDB IDs		6ZOT	2YDX 2YDY 4KTT 4KTV 4NDN
Enriched GO Terms of Interacting Partners?
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