DEFB116 and POFUT1

		DEFB116	POFUT1
Description		defensin beta 116	protein O-fucosyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Endoplasmic Reticulum Membrane
	Molecular Function		Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Defense Response To Bacterium Innate Immune Response	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation
Pathways		Beta defensins Defensins	Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		Prudent dietary pattern ( 28644415) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes			4 interacting genes: AKT2 DLL1 JAG1 NOTCH1
Entrez ID		245930	23509
HPRD ID		19020	06319
Ensembl ID		ENSG00000215545	ENSG00000101346
Uniprot IDs		Q30KQ4	Q9H488
PDB IDs			5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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