DEFB115 and POFUT1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		DEFB115	POFUT1
Description		defensin beta 115	protein O-fucosyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Defense Response To Bacterium Innate Immune Response	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation
Pathways		Beta defensins Defensins	Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		Prudent dietary pattern ( 28644415)	Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes		2 interacting genes: UBQLN1 UBQLN2	4 interacting genes: AKT2 DLL1 JAG1 NOTCH1
Entrez ID		245929	23509
HPRD ID		18944	06319
Ensembl ID		ENSG00000215547	ENSG00000101346
Uniprot IDs		Q30KQ5	Q9H488
PDB IDs			5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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