IL17RA and BCL2L13

Data Source:
BioGRID (affinity chromatography technology)

		IL17RA	BCL2L13
Description		interleukin 17 receptor A	BCL2 like 13
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Interleukin-17 Receptor Activity	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Adaptive Immune Response Inflammatory Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Interleukin-23 Production Positive Regulation Of Interleukin-6 Production Innate Immune Response Fibroblast Activation Interleukin-17-mediated Signaling Pathway Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Apoptotic Process
Pathways		Interleukin-17 signaling
Drugs
Diseases		Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS		Blood protein levels ( 30072576 29875488 28240269) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Granulocyte percentage of myeloid white cells ( 27863252) Heschl's gyrus morphology ( 25130324) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) White blood cell count ( 32888494 27863252)	Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Hemoglobin levels ( 32327693) Interleukin-10 levels ( 22205395) Lymphocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: IL17A MTDH	55 interacting genes: ADIPOQ AGTRAP AIG1 APOD APP AQP1 BET1 C4orf3 CD53 CLDN19 CRB3 DEFB127 ERG28 ERMP1 FAM210B FXYD3 FZD7 GABARAPL2 GALNT2 GAST HMOX2 JAGN1 LAT LPAR3 MAL MTNR1B NINJ2 PLLP PLN PLP1 PLPP4 SLC30A8 SLC35A1 SLC35G5 SMIM1 SPOCK1 STX12 STX8 TM6SF2 TMEM128 TMEM14C TMEM242 TMEM254 TMEM51 TMEM72 TMEM86A TMEM86B TMEM97 TMUB2 TNF TNMD TRARG1 UPK1B VAMP3 VAMP4
Entrez ID		23765	23786
HPRD ID		10399	09822
Ensembl ID		ENSG00000177663	ENSG00000099968
Uniprot IDs		Q96F46	A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F6VJB4 Q86T62 Q9BXK5
PDB IDs		3JVF 4HSA 4NUX 5N9B 5NAN	2IPD
Enriched GO Terms of Interacting Partners?
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