PLA2G15 and EDC4

Data Source:
BioGRID (affinity chromatography technology)

		PLA2G15	EDC4
Description		phospholipase A2 group XV	enhancer of mRNA decapping 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Lysophospholipase Activity Triglyceride Lipase Activity Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phosphatidyl Phospholipase B Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Protein Binding
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways		Hydrolysis of LPC	mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		2 interacting genes: IMMT RNF7	38 interacting genes: CCL5 CDC42 EIF2AK2 FBLN1 GIT2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR122 MIR128-2 MIR141 MIR15B MIR199A1 MIR200A MIR200B MIR200C MIR205 MIR20A MIR21 MIR214 MIR222 MIR29C MIR34A MIR34C MIR363 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E SUMO2 YTHDC1
Entrez ID		23659	23644
HPRD ID		07128	06911
Ensembl ID		ENSG00000103066	ENSG00000038358
Uniprot IDs		Q8NCC3	Q6P2E9
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW
Enriched GO Terms of Interacting Partners?
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