DNAAF11 and ST3GAL1

Data Source:
HPRD (in vivo)

		DNAAF11	ST3GAL1
Description		dynein axonemal assembly factor 11	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Cilium Apical Cytoplasm	Golgi Membrane Membrane Integral Component Of Membrane Trans-Golgi Network Membrane Extracellular Exosome Golgi Medial Cisterna Membrane Golgi Trans Cisterna Membrane
	Molecular Function	Molecular_function Protein Binding	Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity Monosialoganglioside Sialyltransferase Activity
	Biological Process	Cilium Movement Male Gonad Development Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Regulation Of Protein Binding Motile Cilium Assembly Establishment Of Localization In Cell Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Reproductive System Development Protein Localization To Cilium Cerebrospinal Fluid Circulation	Memory B Cell Differentiation N-acetylneuraminate Metabolic Process Cellular Protein Modification Process Protein Phosphorylation Protein N-linked Glycosylation Ganglioside Biosynthetic Process Via Lactosylceramide O-glycan Processing Keratan Sulfate Biosynthetic Process Sialylation Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process Protein Sialylation
Pathways			Keratan sulfate biosynthesis Sialic acid metabolism Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Frontal fibrosing alopecia ( 30850646) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Intraocular pressure ( 24002674) Personality dimensions ( 23903073) Problematic alcohol use in trauma-exposed individuals ( 29082582) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Schizophrenia (negative symptoms) ( 23382809) Squamous cell carcinoma ( 26908436)
Interacting Genes		10 interacting genes: DDX6 LRCH3 LSM2 MEOX2 PLEKHF2 PODN SSX7 TERF1 TSC22D2 TTC23L	1 interacting genes: GSTA1
Entrez ID		23639	6482
HPRD ID		10286	06219
Ensembl ID		ENSG00000129295	ENSG00000008513
Uniprot IDs		Q86X45	A0A024R9L6 Q11201
PDB IDs
Enriched GO Terms of Interacting Partners?
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