FPR1 and KIR3DL1

Data Source:
BioGRID (affinity chromatography technology)

		FPR1	KIR3DL1
Description		formyl peptide receptor 1	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Binding Complement Receptor Activity G Protein-coupled Receptor Activity N-formyl Peptide Receptor Activity Scavenger Receptor Binding Protein Binding RAGE Receptor Binding	Amyloid-beta Binding Protein Binding HLA-B Specific Inhibitory MHC Class I Receptor Activity
	Biological Process	Activation Of MAPK Activity Complement Receptor Mediated Signaling Pathway Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Nitric Oxide Mediated Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Degranulation	Immune Response Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Interleukin-10 signaling Neutrophil degranulation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Nedocromil
Diseases
GWAS		Alopecia areata ( 25608926) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Tourette syndrome ( 30818990)	Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: ACTG1 ANXA1 GNAI2 GRK2 SAA1	6 interacting genes: BMP10 CDK3 HLA-B RPS6KB1 SMCO4 THSD7B
Entrez ID		2357	3811
HPRD ID		00646	09226
Ensembl ID		ENSG00000171051	ENSG00000167633
Uniprot IDs		P21462	P43629 Q5UCE2 Q6H2G3 Q8N6C9
PDB IDs			3VH8 3WUW 5B38 5B39 5T6Z 5T70 6V3J
Enriched GO Terms of Interacting Partners?
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