GTPBP4 and PTGFR

Data Source:
BioGRID (biochemical)

		GTPBP4	PTGFR
Description		GTP binding protein 4	prostaglandin F receptor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding	Prostaglandin F Receptor Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Osteoblast Differentiation Negative Regulation Of DNA Replication Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell-cell Adhesion Negative Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Negative Regulation Of Collagen Binding Protein Stabilization	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus
Pathways			Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases
GWAS		Height ( 28552196)	Bipolar disorder ( 22182935) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		3 interacting genes: COPB1 SRPK2 YWHAG	5 interacting genes: AGTR1 PTGDS PTGER1 PTGER2 PTGES2
Entrez ID		23560	5737
HPRD ID		09976	08988
Ensembl ID		ENSG00000107937	ENSG00000122420
Uniprot IDs		D2CFK9 Q9BZE4	P43088
PDB IDs		6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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