ATP6V0A2 and MPHOSPH9

Data Source:
HPRD (in vivo, in vitro)

		ATP6V0A2	MPHOSPH9
Description		ATPase H+ transporting V0 subunit a2	M-phase phosphoprotein 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Acrosomal Vesicle Lysosomal Membrane Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Perinuclear Region Of Cytoplasm	Golgi Membrane Golgi Apparatus Centriole Membrane
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Cellular Iron Ion Homeostasis Immune Response Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs		Tiludronic acid
Diseases		Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Adiponectin levels ( 22479202) Neutrophil count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Albumin-globulin ratio ( 29403010) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Intelligence (MTAG) ( 29326435) Multiple sclerosis ( 19525953) Plasma anti-thyroglobulin levels ( 29678681) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 24509480 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Venous thromboembolism ( 31420334)
Interacting Genes		2 interacting genes: CYTH2 DRD2	3 interacting genes: SVIL YWHAG YWHAZ
Entrez ID		23545	10198
HPRD ID		16521	12022
Ensembl ID		ENSG00000185344	ENSG00000051825
Uniprot IDs		Q9Y487	Q99550
PDB IDs
Enriched GO Terms of Interacting Partners?
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