POFUT1 and NAP1L2

Data Source:
BioGRID (proximity labelling technology)

		POFUT1	NAP1L2
Description		protein O-fucosyltransferase 1	nucleosome assembly protein 1 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Chromatin Nucleus
	Molecular Function	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation	Nucleosome Assembly Positive Regulation Of Neuron Differentiation Positive Regulation Of Histone H3-K14 Acetylation Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation
Pathways		Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)	Bipolar disorder ( 31043756)
Interacting Genes		4 interacting genes: AKT2 DLL1 JAG1 NOTCH1	13 interacting genes: CCDC146 CCDC185 DMAP1 FAM81A KLHL2 MED30 NAP1L1 NAP1L5 PPP1R13B PPP3R1 SCNM1 SH3BP5 SP110
Entrez ID		23509	4674
HPRD ID		06319	02066
Ensembl ID		ENSG00000101346	ENSG00000186462
Uniprot IDs		Q9H488	Q9ULW6
PDB IDs		5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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