POFUT1 and DEFB115

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		POFUT1	DEFB115
Description		protein O-fucosyltransferase 1	defensin beta 115
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Extracellular Region
	Molecular Function	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity	Protein Binding
	Biological Process	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation	Defense Response To Bacterium Innate Immune Response
Pathways		Pre-NOTCH Processing in the Endoplasmic Reticulum	Beta defensins Defensins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)	Prudent dietary pattern ( 28644415)
Interacting Genes		4 interacting genes: AKT2 DLL1 JAG1 NOTCH1	2 interacting genes: UBQLN1 UBQLN2
Entrez ID		23509	245929
HPRD ID		06319	18944
Ensembl ID		ENSG00000101346	ENSG00000215547
Uniprot IDs		Q9H488	Q30KQ5
PDB IDs		5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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