LARS2 and RASSF1

Data Source:
BioGRID (affinity chromatography technology)

		LARS2	RASSF1
Description		leucyl-tRNA synthetase 2, mitochondrial	Ras association domain family member 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton
	Molecular Function	Aminoacyl-tRNA Editing Activity Leucine-tRNA Ligase Activity ATP Binding	Protein Binding Zinc Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Leucyl-tRNA Aminoacylation Mitochondrial Translation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Cell Cycle Arrest Signal Transduction Ras Protein Signal Transduction Regulation Of Microtubule Cytoskeleton Organization
Pathways		Mitochondrial tRNA aminoacylation
Drugs		Leucine
Diseases			Non-small cell lung cancer Bladder cancer Nasopharyngeal cancer
GWAS		Acne (severe) ( 24927181) Adult body size ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Inflammatory skin disease ( 25574825) Pre-treatment viral load in HIV-1 infection ( 31219150) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Basophil percentage of white cells ( 32888494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: RHOU YWHAQ	70 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SAV1 SMARCA4 STK11 STK3 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA
Entrez ID		23395	11186
HPRD ID		05178	05470
Ensembl ID		ENSG00000011376	ENSG00000068028
Uniprot IDs		Q15031	Q9NS23
PDB IDs			2KZU
Enriched GO Terms of Interacting Partners?
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