PMPCA and SCUBE1

Data Source:
BioGRID (affinity chromatography technology)

		PMPCA	SCUBE1
Description		peptidase, mitochondrial processing subunit alpha	signal peptide, CUB domain and EGF like domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Extrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Identical Protein Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Inflammatory Response Signal Transduction Adult Heart Development Blood Coagulation Post-embryonic Development Extracellular Matrix Disassembly Endothelial Cell Differentiation Positive Regulation Of Smoothened Signaling Pathway
Pathways		Mitochondrial protein import Processing of SMDT1	Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)	Blood protein levels ( 30072576) Molar-incisor hypomineralization ( 23918034) Response to fenofibrate (adiponectin levels) ( 23149075) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		5 interacting genes: BMPR2 LINC01554 PMPCB SKIV2L ZNF76	2 interacting genes: SCUBE2 SCUBE3
Entrez ID		23203	80274
HPRD ID		07500	18029
Ensembl ID		ENSG00000165688	ENSG00000159307
Uniprot IDs		Q10713	A0JP65 Q6ZS56 Q86TI6 Q8IWY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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