PMPCA and AVEN

Data Source:
BioGRID (affinity chromatography technology)

		PMPCA	AVEN
Description		peptidase, mitochondrial processing subunit alpha	apoptosis and caspase activation inhibitor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Cytosol Endomembrane System Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Apoptotic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Apoptotic Process
Pathways		Mitochondrial protein import Processing of SMDT1	Formation of apoptosome Regulation of the apoptosome activity
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)	Malaria ( 31844061)
Interacting Genes		5 interacting genes: BMPR2 LINC01554 PMPCB SKIV2L ZNF76	3 interacting genes: APAF1 BCL2L1 SMURF1
Entrez ID		23203	57099
HPRD ID		07500	05588
Ensembl ID		ENSG00000165688	ENSG00000169857
Uniprot IDs		Q10713	Q9NQS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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