PMPCA and NDOR1

Data Source:
BioGRID (affinity chromatography technology)

		PMPCA	NDOR1
Description		peptidase, mitochondrial processing subunit alpha	NADPH dependent diflavin oxidoreductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Cell Death Iron-sulfur Cluster Assembly Cellular Response To Menadione
Pathways		Mitochondrial protein import Processing of SMDT1	Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)	Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		5 interacting genes: BMPR2 LINC01554 PMPCB SKIV2L ZNF76	30 interacting genes: C7orf57 CCDC33 CENATAC CIAPIN1 CYCS DLG4 EFHC2 ENOX2 GAS8 GPS2 HOXB2 KIAA0408 LMO2 LMO3 LNX1 MEOX1 MTUS2 NAB2 NLK PSMB6 TCF4 TCHP TEPSIN TLE5 UBQLN1 UBQLN2 ZBTB42 ZC2HC1C ZNF620 ZNF774
Entrez ID		23203	27158
HPRD ID		07500	10444
Ensembl ID		ENSG00000165688	ENSG00000188566
Uniprot IDs		Q10713	Q9UHB4
PDB IDs			4H2D
Enriched GO Terms of Interacting Partners?
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