GPD1L and DYNC1LI1

Data Source:
BioGRID (enzymatic study)

		GPD1L	DYNC1LI1
Description		glycerol-3-phosphate dehydrogenase 1 like	dynein cytoplasmic 1 light intermediate chain 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Glycerol-3-phosphate Dehydrogenase Complex Extracellular Exosome	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Centrosome Cytosol Cytoplasmic Dynein Complex Microtubule Plasma Membrane Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Glycerol-3-phosphate Dehydrogenase [NAD+] Activity Sodium Channel Regulator Activity Protein Homodimerization Activity Ion Channel Binding NAD Binding	RNA Binding Motor Activity Protein Binding ATP Binding GTP Binding GDP Binding Dynein Heavy Chain Binding
	Biological Process	Regulation Of Heart Rate Carbohydrate Metabolic Process NADH Oxidation Phosphatidic Acid Biosynthetic Process Positive Regulation Of Sodium Ion Transport NAD Metabolic Process Negative Regulation Of Peptidyl-serine Phosphorylation Glycerol-3-phosphate Catabolic Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Protein Kinase C Signaling Positive Regulation Of Protein Localization To Cell Surface Regulation Of Sodium Ion Transmembrane Transporter Activity	Microtubule Cytoskeleton Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Cell Cycle Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Neutrophil Degranulation Cell Division Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways		Synthesis of PA	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Brugada syndrome (BRS)
GWAS		Alcohol dependence ( 22004471) Periodontal disease-related phenotype (Socransky) ( 24347629) Schizophrenia ( 28991256)	Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes			7 interacting genes: BRCA2 IKBKG NOP56 NUP85 PGAM2 RAB4A REL
Entrez ID		23171	51143
HPRD ID		10008	10917
Ensembl ID		ENSG00000152642	ENSG00000144635
Uniprot IDs		Q8N335	E9PHI6 Q9Y6G9
PDB IDs		2PLA	6B9H 6PSE
Enriched GO Terms of Interacting Partners?
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