EMC1 and AKR7A2

Data Source:
BioGRID (biochemical)

		EMC1	AKR7A2
Description		ER membrane protein complex subunit 1	aldo-keto reductase family 7 member A2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex EMC Complex	Golgi Apparatus Cytosol Extracellular Exosome
	Molecular Function	Membrane Insertase Activity	Alditol:NADP+ 1-oxidoreductase Activity Protein Binding Electron Transfer Activity Phenanthrene-9,10-epoxide Hydrolase Activity
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane	Carbohydrate Metabolic Process Cellular Aldehyde Metabolic Process Xenobiotic Metabolic Process Electron Transport Chain Daunorubicin Metabolic Process Doxorubicin Metabolic Process
Pathways			Aflatoxin activation and detoxification
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes			5 interacting genes: AKR7A3 F2 MCPH1 TRIM63 ZBTB1
Entrez ID		23065	8574
HPRD ID		08306	04567
Ensembl ID		ENSG00000127463	ENSG00000053371
Uniprot IDs		Q8N766	B4DZX4 O43488 V9HWA2
PDB IDs		6WW7 6Z3W	2BP1
Enriched GO Terms of Interacting Partners?
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