SORCS3 and ACSM6

Data Source:
BioGRID (two hybrid)

		SORCS3	ACSM6
Description		sortilin related VPS10 domain containing receptor 3	acyl-CoA synthetase medium chain family member 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Mitochondrial Matrix
	Molecular Function	Protein Binding Neuropeptide Receptor Activity	Fatty-acyl-CoA Synthase Activity ATP Binding GTP Binding Fatty Acid Ligase Activity Medium-chain Fatty Acid-CoA Ligase Activity Metal Ion Binding Butyrate-CoA Ligase Activity
	Biological Process	Neuropeptide Signaling Pathway Learning Memory Regulation Of Long-term Synaptic Depression	Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Acyl-CoA Metabolic Process
Pathways			Beta oxidation of butanoyl-CoA to acetyl-CoA
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Attention deficit hyperactivity disorder ( 30478444) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Depression ( 29700475) Diabetic kidney disease ( 26305897) Diastolic blood pressure ( 30224653) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Mood instability ( 31168069) Multisite chronic pain ( 31194737) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) Rosacea symptom severity ( 29771307) Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Systolic blood pressure ( 30578418)	Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		2 interacting genes: ATXN1 NGF
Entrez ID		22986	142827
HPRD ID		12100	12565
Ensembl ID		ENSG00000156395	ENSG00000173124
Uniprot IDs		Q86XB2 Q9UPU3	Q6P461
PDB IDs
Enriched GO Terms of Interacting Partners?
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