EFR3B and IFT172

Data Source:
BioGRID (enzymatic study)

		EFR3B	IFT172
Description		EFR3 homolog B	intraflagellar transport 172
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Actin Cytoskeleton	Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet Extracellular Vesicle
	Molecular Function	Protein Binding
	Biological Process	Phosphatidylinositol Phosphorylation Protein Localization To Plasma Membrane	Neural Tube Closure Heart Looping Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Limb Development Cilium Assembly Bone Development Hindgut Development Left/right Axis Specification Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index in non-asthmatics ( 23517042) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 28552196) Inflammatory bowel disease ( 28067908) Type 1 diabetes ( 21980299)	Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Total cholesterol levels ( 30718733)
Interacting Genes			2 interacting genes: LHX3 LHX4
Entrez ID		22979	26160
HPRD ID		13824	09576
Ensembl ID		ENSG00000084710	ENSG00000138002
Uniprot IDs		B3KT90 E7ESK9 Q9Y2G0	A0A6Q8PGJ2 Q9UG01
PDB IDs
Enriched GO Terms of Interacting Partners?
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