VASH1 and NPC2

Data Source:
BioGRID (affinity chromatography technology)

		VASH1	NPC2
Description		vasohibin 1	NPC intracellular cholesterol transporter 2
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Apical Part Of Cell	Extracellular Region Extracellular Space Lysosome Endoplasmic Reticulum Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Actin Binding Metallocarboxypeptidase Activity Protein Binding	Protein Binding Cholesterol Binding Enzyme Binding Sterol Binding Cholesterol Transfer Activity
	Biological Process	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Proteolysis Cell Cycle Arrest Response To Wounding Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Angiogenesis Labyrinthine Layer Blood Vessel Development Negative Regulation Of Lymphangiogenesis Regulation Of Cellular Senescence	Cholesterol Metabolic Process Response To Virus Phospholipid Transport Sterol Transport Regulation Of Isoprenoid Metabolic Process Cholesterol Transport Intracellular Sterol Transport Intracellular Cholesterol Transport Cholesterol Efflux Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Neutrophil Degranulation Glycolipid Transport Intermembrane Lipid Transfer
Pathways		Carboxyterminal post-translational modifications of tubulin	Neutrophil degranulation LDL clearance
Drugs
Diseases			Niemann-Pick type C disease (NPC), including: Niemann-Pick disease, type C1; Niemann-Pick disease, type C2
GWAS			Advanced glycation end-product levels ( 26915486) Blood protein levels ( 29875488) Intraocular pressure ( 31959993) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: DHPS	9 interacting genes: BARD1 BRCA1 DHDDS ECT2 ERRFI1 LIG4 PAXIP1 TRIM14 USP4
Entrez ID		22846	10577
HPRD ID		12353	03008
Ensembl ID		ENSG00000071246	ENSG00000119655
Uniprot IDs		Q7L8A9	A0A024R6C0 P61916
PDB IDs		6J4U 6J7B 6J8F 6J8N 6J8O 6J91 6J9H 6K81 6LPG 6NVQ 6OCF 6OCG 6OCH 6WSL	5KWY 6W5V
Enriched GO Terms of Interacting Partners?
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