GSX1 and PAN3

Data Source:
HPRD (in vivo)

		GSX1	PAN3
Description		GS homeobox 1	poly(A) specific ribonuclease subunit PAN3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	P-body Cytosol PAN Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Poly(A)-specific Ribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Spinal Cord Association Neuron Differentiation Hypothalamus Development Adenohypophysis Development Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Protein Phosphorylation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			Deadenylation of mRNA
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Body mass index ( 26426971) Pancreatic cancer ( 25086665) Plasma parathyroid hormone levels ( 30134803)	Bipolar disorder ( 20351715) Body mass index ( 26426971) Granulocyte percentage of myeloid white cells ( 27863252) Hepcidin/transferrin saturation ratio ( 27846281) Mean corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Pancreatic cancer ( 25086665)
Interacting Genes		1 interacting genes: KRTAP19-7	4 interacting genes: PABPC1 PAN2 SVIL TNRC6B
Entrez ID		219409	255967
HPRD ID		11016	17818
Ensembl ID		ENSG00000169840	ENSG00000152520
Uniprot IDs		Q9H4S2	Q58A45
PDB IDs
Enriched GO Terms of Interacting Partners?
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