USP12 and NUP58

Data Source:
BioGRID (proximity labelling technology)

		USP12	NUP58
Description		ubiquitin specific peptidase 12	nucleoporin 58
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GO Annotations	Cellular Component	Cellular_component Nucleus Nucleoplasm Cytosol	Nuclear Envelope Nuclear Pore Nuclear Membrane Host Cell
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metal Ion Binding	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Protein Import Into Nucleus Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Alcohol dependence ( 21314694) Anti-saccade response ( 29064472) Mortality in sepsis ( 27639821) Nose morphology ( 29921221) Ulcerative colitis ( 19915573)
Interacting Genes		6 interacting genes: APP H2AC20 H2BC21 NOTCH1 UBC WDR20	19 interacting genes: ABI3 AGR2 APC COG3 COG6 HTT KRT27 KRT28 KRT33B MAPK3 MEIS2 MIS18A NUP62 PKNOX1 PKNOX2 TRAF1 TRIM54 UBQLN1 UBQLN2
Entrez ID		219333	9818
HPRD ID		15631	06355
Ensembl ID		ENSG00000152484	ENSG00000139496
Uniprot IDs		O75317	Q9BVL2
PDB IDs		5K16 5K1A 5K1B 5K1C 5L8W	4JO7 4JO9 4JQ5 5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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