ELAVL2 and IL11RA

Data Source:
BioGRID (biochemical)

		ELAVL2	IL11RA
Description		ELAV like RNA binding protein 2	interleukin 11 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Ribonucleoprotein Complex	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Interleukin-11 Receptor Activity Protein Binding Cytokine Binding Interleukin-11 Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated	Positive Regulation Of Cell Population Proliferation Cytokine-mediated Signaling Pathway Developmental Process Interleukin-11-mediated Signaling Pathway Head Development
Pathways		mRNA Splicing - Major Pathway	IL-6-type cytokine receptor ligand interactions
Drugs			Oprelvekin
Diseases
GWAS		Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27089181 29255261 27067015) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929)	Blood protein levels ( 29875488) CTACK levels ( 27989323)
Interacting Genes		6 interacting genes: ELAVL3 ELAVL4 HNRNPAB HOXC9 NR2E3 RBFOX2	2 interacting genes: IL11 OLFM4
Entrez ID		1993	3590
HPRD ID		03396	02965
Ensembl ID		ENSG00000107105	ENSG00000137070
Uniprot IDs		A0A0A0MRX1 Q12926	Q14626 Q5VZ79
PDB IDs			6O4P
Enriched GO Terms of Interacting Partners?
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