ANO6 and C12orf40

Data Source:
BioGRID (enzymatic study)

		ANO6	C12orf40
Description		anoctamin 6	chromosome 12 open reading frame 40
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity	Protein Binding
	Biological Process	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways		Stimuli-sensing channels Neutrophil degranulation
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)	Parkinson's disease ( 28011712)
Interacting Genes			5 interacting genes: DYNLL1 DYNLL2 LMO4 NXF1 TNPO2
Entrez ID		196527	283461
HPRD ID		18746	08806
Ensembl ID		ENSG00000177119	ENSG00000180116
Uniprot IDs		B3KX12 Q4KMQ2	Q86WS4
PDB IDs
Enriched GO Terms of Interacting Partners?
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