ANO6 and CPNE8

Data Source:
BioGRID (affinity chromatography technology)

		ANO6	CPNE8
Description		anoctamin 6	copine 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Plasma Membrane Extracellular Exosome
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity	Molecular_function Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Biological_process Cellular Response To Calcium Ion
Pathways		Stimuli-sensing channels Neutrophil degranulation
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Arterial stiffness index ( 31235810) Bipolar disorder ( 28115744) Bisphosphonate-associated atypical femoral fracture ( 31006051) Bitter alcoholic beverage consumption ( 31046077) Body mass index ( 25673413) Body size at age 10 ( 32376654) Chronotype ( 30696823) Heart rate ( 23583979) Heart rate response to recovery post exercise ( 29769521) Irritable bowel syndrome ( 29626450) Morning person ( 30696823) Resting heart rate ( 29769521)
Interacting Genes			2 interacting genes: NECAB1 SORBS3
Entrez ID		196527	144402
HPRD ID		18746	16747
Ensembl ID		ENSG00000177119	ENSG00000139117
Uniprot IDs		B3KX12 Q4KMQ2	Q86YQ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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