ANO6 and ALG10B

Data Source:
BioGRID (affinity chromatography technology)

		ANO6	ALG10B
Description		anoctamin 6	ALG10 alpha-1,2-glucosyltransferase B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity	Protein Binding Transferase Activity Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity
	Biological Process	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Protein Glycosylation Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Positive Regulation Of Protein Glycosylation Positive Regulation Of Inward Rectifier Potassium Channel Activity
Pathways		Stimuli-sensing channels Neutrophil degranulation	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)	Chronotype ( 30696823) Drug-induced liver injury (flucloxacillin) ( 19483685) Heart rate response to recovery post exercise ( 29769521) Idiopathic dilated cardiomyopathy ( 29495422) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Resting heart rate ( 27798624) Triglyceride levels ( 32203549)
Interacting Genes			3 interacting genes: CD79A KCNH2 SHISAL1
Entrez ID		196527	144245
HPRD ID		18746	11923
Ensembl ID		ENSG00000177119	ENSG00000175548
Uniprot IDs		B3KX12 Q4KMQ2	Q5I7T1
PDB IDs
Enriched GO Terms of Interacting Partners?
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