ANO6 and SLC2A13

Data Source:
BioGRID (affinity chromatography technology)

		ANO6	SLC2A13
Description		anoctamin 6	solute carrier family 2 member 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Cytoplasm Lysosome Early Endosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Growth Cone Organelle Membrane Cell Projection Intracellular Membrane-bounded Organelle Cell Body Cell Periphery Astrocyte End-foot
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity	Protease Binding Myo-inositol Transmembrane Transporter Activity Myo-inositol:proton Symporter Activity Protein Binding ATPase Binding
	Biological Process	Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Myo-inositol Transport Transmembrane Transport Transport Across Blood-brain Barrier Positive Regulation Of Amyloid-beta Formation
Pathways		Stimuli-sensing channels Neutrophil degranulation	Inositol transporters
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)	Alzheimer's disease in hypertension ( 31055733) Coronary artery calcification ( 23870195) Crohn's disease ( 28067908) Daytime sleep phenotypes ( 27126917) Disability (impaired activities of daily living) ( 31707593) Inflammatory bowel disease ( 28067908) Insomnia ( 23728906) Parkinson's disease ( 22451204 32201043 28011712) Putamen volume ( 31530798) Sleep quality ( 23728906)
Interacting Genes			4 interacting genes: CYP4F2 FXYD6-FXYD2 PLP2 RIC8A
Entrez ID		196527	114134
HPRD ID		18746	15363
Ensembl ID		ENSG00000177119	ENSG00000151229
Uniprot IDs		B3KX12 Q4KMQ2	Q96QE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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