TOR1A and ENPP2

Data Source:
BioGRID (affinity chromatography technology)

		TOR1A	ENPP2
Description		torsin family 1 member A	ectonucleotide pyrophosphatase/phosphodiesterase 2
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GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Cytoskeleton Synaptic Vesicle Membrane Secretory Granule Growth Cone Cytoplasmic Vesicle Membrane Nuclear Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Space Plasma Membrane
	Molecular Function	Protein Binding ATP Binding Cytoskeletal Protein Binding ATPase Activity Kinesin Binding Identical Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Nucleic Acid Binding Phosphodiesterase I Activity Nucleotide Diphosphatase Activity Lysophospholipase Activity Scavenger Receptor Activity Calcium Ion Binding Transcription Factor Binding Zinc Ion Binding Hydrolase Activity Polysaccharide Binding Alkylglycerophosphoethanolamine Phosphodiesterase Activity
	Biological Process	Protein Deneddylation Response To Oxidative Stress Organelle Organization Nuclear Envelope Organization Cell Adhesion Neuron Projection Development Protein Localization To Nucleus Wound Healing, Spreading Of Cells Intermediate Filament Cytoskeleton Organization Synaptic Vesicle Transport Chaperone Cofactor-dependent Protein Refolding Regulation Of Dopamine Uptake Involved In Synaptic Transmission Chaperone-mediated Protein Folding ER-associated Misfolded Protein Catabolic Process Nuclear Membrane Organization Chaperone-mediated Protein Transport Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Localization To Cell Surface	Endocytosis Chemotaxis Immune Response Phospholipid Catabolic Process Positive Regulation Of Epithelial Cell Migration Sphingolipid Catabolic Process Regulation Of Cell Migration Phosphatidylcholine Catabolic Process Regulation Of Angiogenesis Cell Motility Positive Regulation Of Peptidyl-tyrosine Phosphorylation Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Lamellipodium Morphogenesis
Pathways		Cargo recognition for clathrin-mediated endocytosis	Vitamin B5 (pantothenate) metabolism
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016)	Appendicular lean mass ( 33097823) Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 31562340) Offspring birth weight ( 31043758)
Interacting Genes		7 interacting genes: KRTAP10-7 LMNA LRRC7 MDFI SNCA TOR1AIP2 TOR1B	1 interacting genes: HSPB1
Entrez ID		1861	5168
HPRD ID		06897	03037
Ensembl ID		ENSG00000136827	ENSG00000136960
Uniprot IDs		B3KPA1 O14656	E7EUF1 Q13822
PDB IDs		5J1S 5J1T 6OIF	4ZG6 4ZG7 4ZG9 4ZGA 5KXA 5M7M 5MHP
Enriched GO Terms of Interacting Partners?
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