DSC3 and DSC2

Data Source:
HPRD (in vitro)

		DSC3	DSC2
Description		desmocollin 3	desmocollin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Cytoplasm Plasma Membrane Cell-cell Junction Membrane Integral Component Of Membrane Cell Junction Desmosome	Cornified Envelope Plasma Membrane Cell-cell Junction Adherens Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Calcium Ion Binding Gamma-catenin Binding	Calcium Ion Binding Protein Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
	Biological Process	In Utero Embryonic Development Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Keratinization Cornification Cell-cell Adhesion	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Response To Starvation Keratinization Cornification Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases		Hypotrichosis and recurrent skin vesicles	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS		Bronchopulmonary dysplasia ( 23897914) Hand grip strength (Mahalanobis distance) ( 32235003) Metabolite levels ( 31628463) Obesity-related traits ( 23251661) Protein quantitative trait loci ( 18464913) Supraventricular ectopy ( 29618737) Type 2 diabetes ( 31049640)	Blood protein levels ( 30072576 29875488) Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: CTNNB1 JUP PKP3 PKP4 UCHL5	6 interacting genes: CLK1 DSG1 DSG2 JUP PKP2 PKP3
Entrez ID		1825	1824
HPRD ID		02604	00512
Ensembl ID		ENSG00000134762	ENSG00000134755
Uniprot IDs		Q14574	A0A3B3ISU0 Q02487
PDB IDs			5ERP 5J5J
Enriched GO Terms of Interacting Partners?
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