DSC2 and FHOD3

Data Source:
HPRD (in vitro)

		DSC2	FHOD3
Description		desmocollin 2	formin homology 2 domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Plasma Membrane Cell-cell Junction Adherens Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Exosome	Cytoplasm Cytoskeleton Striated Muscle Thin Filament Z Disc
	Molecular Function	Calcium Ion Binding Protein Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication	Protein Binding Actin Filament Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Response To Starvation Keratinization Cornification Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential	Negative Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Sarcomere Organization Actin Filament Network Formation Cardiac Myofibril Assembly
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS		Blood protein levels ( 30072576 29875488) Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 23823483)	Adverse response to drug ( 30420678) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Height ( 31562340) Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 24347629) Pulse pressure ( 27841878 30578418) QRS duration ( 27659466) Response to antipsychotic treatment ( 20195266) Resting heart rate ( 29769521 27798624) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		6 interacting genes: CLK1 DSG1 DSG2 JUP PKP2 PKP3
Entrez ID		1824	80206
HPRD ID		00512	16894
Ensembl ID		ENSG00000134755	ENSG00000134775
Uniprot IDs		A0A3B3ISU0 Q02487	Q2V2M9
PDB IDs		5ERP 5J5J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?