DIO3 and CKB

Data Source:
BioGRID (genetic interference)

		DIO3	CKB
Description		iodothyronine deiodinase 3	creatine kinase B
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endosome Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Nucleus Cytosol Dendrite Neuronal Cell Body Extracellular Exosome
	Molecular Function	Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Ubiquitin Protein Ligase Binding
	Biological Process	Thyroid Hormone Generation Positive Regulation Of Multicellular Organism Growth Thyroid Hormone Metabolic Process Thyroid Hormone Catabolic Process Hormone Biosynthetic Process Negative Regulation Of Eye Photoreceptor Cell Development Retinal Cone Cell Development Retinal Cone Cell Apoptotic Process	Creatine Metabolic Process Phosphorylation Cerebellum Development Substantia Nigra Development Cellular Chloride Ion Homeostasis Phosphocreatine Biosynthetic Process
Pathways		Regulation of thyroid hormone activity	Creatine metabolism
Drugs		Iopodic acid	Creatine Phosphocreatine
Diseases
GWAS		Metabolite levels ( 23823483) Pulse pressure ( 30224653) Type 1 diabetes ( 19966805)	Adult body size ( 32376654) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Extremely high intelligence ( 29520040) Height ( 28552196 31562340) Schizophrenia ( 25056061)
Interacting Genes		3 interacting genes: APP PRMT5 PRMT7	15 interacting genes: ACD ARIH2 ASB9 CKM ERBB2 GOLGA2 ILK MLH1 POT1 PPP1CA SERP2 TAB1 TERF1 TINF2 TRIM63
Entrez ID		1735	1152
HPRD ID		11867	00423
Ensembl ID		ENSG00000197406	ENSG00000166165
Uniprot IDs		P55073 Q86TU3	G3V4N7 P12277 V9HWH2
PDB IDs			3B6R 3DRB 3DRE 6V9H
Enriched GO Terms of Interacting Partners?
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