DIO1 and ARTN

		DIO1	ARTN
Description		iodothyronine deiodinase 1	artemin
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Thyroxine 5'-deiodinase Activity Selenium Binding	Signaling Receptor Binding Protein Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding
	Biological Process	Cellular Amino Acid Metabolic Process Thyroid Hormone Generation Thyroid Hormone Metabolic Process Hormone Biosynthetic Process	MAPK Cascade Signal Transduction Neuroblast Proliferation Axon Guidance Peripheral Nervous System Development Induction Of Positive Chemotaxis Peyer's Patch Morphogenesis Lymphocyte Migration Into Lymphoid Organs
Pathways		Regulation of thyroid hormone activity	NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Free thyroxine concentration ( 25743335) Thyroid hormone levels ( 23408906)	Autism spectrum disorder or schizophrenia ( 28540026) Tea consumption ( 31046077)
Interacting Genes			1 interacting genes: GFRA3
Entrez ID		1733	9048
HPRD ID		01002	04863
Ensembl ID		ENSG00000211452	ENSG00000117407
Uniprot IDs		A8K415 P49895	Q5T4W7
PDB IDs			2ASK 2GH0 2GYR 2GYZ 6Q2S
Enriched GO Terms of Interacting Partners?
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