ASXL1 and MRPS7

Data Source:
BioGRID (affinity chromatography technology)

		ASXL1	MRPS7
Description		ASXL transcriptional regulator 1	mitochondrial ribosomal protein S7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm PR-DUB Complex	Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding	RNA Binding MRNA Binding Structural Constituent Of Ribosome RRNA Binding
	Biological Process	Cell Morphogenesis Heart Morphogenesis Transcription, DNA-templated Animal Organ Morphogenesis Negative Regulation Of Lipid Storage Protein Deubiquitination Hemopoiesis Response To Retinoic Acid Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Monoubiquitinated Histone H2A Deubiquitination Regulation Of Kidney Size Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Thymus Development Bone Marrow Development Homeostasis Of Number Of Cells Lung Saccule Development Glomerular Visceral Epithelial Cell Development	Ribosomal Small Subunit Assembly Translation Mitochondrial Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		UCH proteinases	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases		C syndrome, including: Opitz trigonocephaly syndrome; Bohring-Opitz syndrome (BOPS)
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908) Red cell distribution width ( 32888494)
Interacting Genes		6 interacting genes: APP GOLGA6L9 H1-2 SRPK1 STAT3 UBC	1 interacting genes: PTEN
Entrez ID		171023	51081
HPRD ID		16516	17601
Ensembl ID		ENSG00000171456	ENSG00000125445
Uniprot IDs		Q498B9 Q8IXJ9	A0A024R8L0 Q9Y2R9
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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