GSDME and TBX19

Data Source:
BioGRID (two hybrid)

		GSDME	TBX19
Description		gasdermin E	T-box transcription factor 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Integral Component Of Membrane	Chromatin Nucleus
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Cardiolipin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Sensory Perception Of Sound Cell Death Negative Regulation Of Cell Population Proliferation Positive Regulation Of MAPK Cascade Inner Ear Receptor Cell Differentiation Necrotic Cell Death Pyroptosis Cellular Response To Tumor Necrosis Factor Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mesoderm Formation Cell Fate Specification Somitogenesis Heart Morphogenesis Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Pituitary Gland Development Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Deafness, autosomal dominant	Adrenocorticotropic hormone deficiency; Isolated ACDH deficiency (IAD)
GWAS
Interacting Genes		3 interacting genes: ITGB1BP1 PTN TIFA	15 interacting genes: GCM2 HGS HOXC8 IRX6 LONRF1 NEDD9 NR5A1 PITX1 POGZ PRR35 RAB2B TBX6 TFG VENTX ZIC1
Entrez ID		1687	9095
HPRD ID		02996	05214
Ensembl ID		ENSG00000105928	ENSG00000143178
Uniprot IDs		A0A024RA58 A4FVA8 O60443	B3KRD9 O60806
PDB IDs
Enriched GO Terms of Interacting Partners?
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