PKD1L1 and MGAT2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		PKD1L1	MGAT2
Description		polycystin 1 like 1, transient receptor potential channel interacting	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Membrane Calcium Channel Complex Ciliary Membrane Non-motile Cilium	Golgi Membrane Golgi Apparatus Golgi Stack Membrane Integral Component Of Membrane
	Molecular Function	Calcium Channel Activity Protein Binding	Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding Carbohydrate Binding Protein Homodimerization Activity
	Biological Process	Detection Of Nodal Flow Detection Of Mechanical Stimulus Calcium Ion Transmembrane Transport Left/right Axis Specification Cell-cell Adhesion	Protein N-linked Glycosylation Oligosaccharide Biosynthetic Process Protein Phosphopantetheinylation Protein N-linked Glycosylation Via Asparagine
Pathways			Defective MGAT2 causes MGAT2-CDG (CDG-2a) Maturation of spike protein Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Anxiety disorder ( 25390645) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Gut microbiota alpha diversity (Shannon index) ( 33208821) Hepatitis C induced liver fibrosis ( 22841784) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Blood protein levels ( 30072576 29875488)
Interacting Genes		1 interacting genes: CLK1
Entrez ID		168507	4247
HPRD ID		10154	04013
Ensembl ID		ENSG00000158683	ENSG00000168282
Uniprot IDs		Q8TDX9	Q10469
PDB IDs			5VCM 5VCR 5VCS
Enriched GO Terms of Interacting Partners?
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