AGR3 and BZW2

Data Source:
BioGRID (affinity chromatography technology)

		AGR3	BZW2
Description		anterior gradient 3, protein disulphide isomerase family member	basic leucine zipper and W2 domains 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle	Cytoplasm Membrane
	Molecular Function	Dystroglycan Binding Protein Binding	Protein Binding Cadherin Binding
	Biological Process	Biological_process Negative Regulation Of Cell Death	Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Coffee consumption ( 31959922 29367735) Cutaneous malignant melanoma ( 32341527 26237428) Cutaneous squamous cell carcinoma ( 32041948) Diffusing capacity of carbon monoxide ( 30694715) Lung cancer in ever smokers ( 28604730) Melanoma ( 28212542) Refractive error ( 32231278) Residual cognition ( 28441426) Rosacea symptom severity ( 29771307) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432)	Alzheimer's disease (cognitive decline) ( 23535033) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
Interacting Genes		35 interacting genes: AKT1 AP1B1 APC ASB10 BCAR3 CASP8 CATSPER1 CD46 CGRRF1 CNNM3 DAG1 DESI1 EDA2R ERLIN1 ESR2 FXYD3 KRTAP11-1 LIME1 LSM1 LYPD3 MMGT1 NRM NTAQ1 NUP62 PDZK1IP1 PRAF2 PTPN1 SGTA SGTB SPINT1 TGFB1 TIMMDC1 TMEM14B UBQLN1 UBQLN2	6 interacting genes: CDC42 EIF2A EIF2B1 EIF3A GSK3B LINC01554
Entrez ID		155465	28969
HPRD ID		16545	16571
Ensembl ID		ENSG00000173467	ENSG00000136261
Uniprot IDs		Q8TD06	A0A024RA42 Q9Y6E2
PDB IDs		3PH9
Enriched GO Terms of Interacting Partners?
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